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An additional potential limitation applicable to all observational studies is the possibility for residual or uncontrolled confounding.
Image-guided, catheter-based, interstitial brachytherapy is employed by an increasing number of centers since it avoids the tumor size limitation applicable for RFA [ 20, 25, 31].
One potential limitation applicable to all studies that so far evaluated the relationship between iFR and FFR is the fact that all hemodynamic analyses were performed offline.
1 2 7 8 9 10 11 12 13 14 15 An important limitation applicable to previous comparative analyses is that most of the observational studies did not have rigorous inclusion and exclusion criteria, exposure definitions, and outcomes identical to the randomised controlled trials so that lack of randomisation was not the only important difference.
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In England there is no general statute of limitations applicable to criminal actions, although statutes for specific crimes frequently have included time limits.
The soil properties were calibrated to smoothed first derivative MIR spectra using partial least-square regression (PLS), and screening tests were developed for various limitation classes applicable in civil works using the soft independent modeling of class analogy (SIMCA).
The chapter concludes that the living Ziegler-Natta polymerization is mostly useful for the preparation of polyethylene diblock copolymers because of the limitation of applicable catalyst systems and reaction conditions.
This latter limitation is applicable to many validated patient-centred outcome measures.
This problem could be easily remedied if the city agreed to extend the notice period for a reasonable time, like the three-year statute of limitations generally applicable in maritime accident cases.
However, the relative strengths, limitations, and applicable ranges of these approaches have not been clearly defined in the past.
Nevertheless, the indirect method also has limitations, being applicable only to the single method used in the population sample considered in that particular study.
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