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Nitrogen Limitation Adaptation.
NITROGEN LIMITATION ADAPTATION (NLA), designated AtNLA1 in this study, was first identified as a positive regulator for the adaptability of Arabidopsis to nitrogen limitation (Peng et al., 2007), and later analysis of Pi concentration revealed that the early senescence phenotype of atnla mutant plants was due to Pi toxicity (Kant et al., 2011).
MiR827 induced by P limitation negatively regulates the transcript level of NITROGEN LIMITATION ADAPTATION (NLA) in Arabidopsis.
Additionally, phosphate uptake in Arabidopsis seems to be enhanced under low N conditions via a signaling pathway involving miRNAs and the E3 ligase NLA (nitrogen limitation adaptation) [ 49].
Like miR399, miR827 is also highly and specifically induced by P-deficiency and is involved in the regulation of plant P homeostasis by down-regulating its target gene nitrogen limitation adaptation (NLA) in Arabidopsis [ 13].
In Arabidopsis, miR827 is also shown to target the Nitrogen Limitation Adaptation (NLA) gene, thereby playing a pivotal role in regulating Pi homeostasis in a nitrate-dependent fashion [ 29].
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Although these results confirm that adaptation to sulfate limitation proceeds via the amplification of the SUL1 gene, the kinetics of the amplification and the final copy number achieved varied between the replicate evolution experiments, suggesting that each population experienced different evolutionary trajectories over the course of sulfate-limited adaptation.
Their needs were knowledge about the nature of disease, sign and symptoms of disease, physical limitation, nutrition, adaptation and adjustment to chronic illness, social function, anxiety and drug therapy.
Lentil is considered an orphan crop from a genomic perspective [ 3] primarily because of the relatively small production base imposed by climatic limitations to adaptation, the limited research investment in sequencing imposed by technology costs and the relatively large size (~4 Gbp; [ 4]) of the genome.
Several of the phenotypic modifications required in the constantly freezing temperatures of the Southern Ocean appear to involve stable genomic modifications (e.g., deletion of the β-globin locus), which might represent a significant limitation to adaptation to warmer environments (Patarnello et al. 2011).
Such information would help to establish the extent to which older adults maintain or regain their desired levels of function in everyday life – despite an increasing frequency of health conditions, impairments and activity limitations – by adaptation [ 23, 24], the use of aids [ 25- 27], assistance from others [ 28, 29] and changes in perception [ 30, 31].
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