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How do we explain that short telomeres limit the function of tissues of slow turnover?
In general, the influence of different immunosuppressive drugs on NK cell function is of particular interest as it has recently been demonstrated that steroids and calcineurin inhibitors limit the function of IL-2-activated NK cells [28], [29].
In contrast to the bone marrow failure phenotype which is prominent in the setting of short telomeres, our data indicate that telomere reserves limit the function of tissues of relatively slow turnover such as β-cells.
Retinal haemorrhages, for example, could limit the function of the visual pathway and thus affect the normal development of visual function.
Deferiprone could access and limit the function of immune cells that infiltrated the CNS, similar to that observed in vitro (Sweeney et al., 2011).
However, higher stress (10 TU and 20 TU) might limit the function of the behavioral adjustment produced by the intrinsic response mechanisms.
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The National Highway Traffic Safety Administration released guidelines on Tuesday aimed at lessening the risks of "distracted driving," recommending that automakers voluntarily limit the functions of electronic devices built into vehicles.
In a recent speech in China, the former Federal Reserve chairman — and current Obama adviser — Paul Volcker called on the government to limit the functions of any financial institution, like the big banks, that will always be reliant on the taxpayer should they get into trouble.
In order to safeguard the freedom of the individual from government encroachment, Humboldt proposed to limit the functions and the authority of the state.
ABCLibScript limits the function of auto-tuning to numerical computations.
This situation limits the function of public parks as social integrators.
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