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These practices limit the correct localization of the potential brain abnormalities, which should be based on a whole-brain analysis of the differences between patients and controls.
In our trial, long-term outcome was not objective and the limited sample size as well as the fact that a significant percentage of patients received adjuvant radiation therapy might further limit the correct interpretation of any possible effect on outcome.
Numerous kinetic, structural, and theoretical studies have established that DNA polymerases adjust their domain structures to enclose nucleotides in their active sites and then rearrange critical active site residues and substrates for catalysis, with the latter conformational change acting to kinetically limit the correct nucleotide incorporation rate.
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They could have been responsible for the lack of phylogenetic signal that limits the correct grouping of organisms in the V-H+ PPase tree.
Because the precatalytic conformational change associated with these domain motions was rapid (step 5 in Figure 6), a rearrangement of the active site residues was instead proposed to limit the rate of correct nucleotide incorporation (step 6 in Figure 6).
Surgeries, when performed, are usually done to limit the presenting symptoms or correct bone defects [ 61].
In order to obtain reproducible 100% error correction while avoiding additional mutations, we found it necessary to limit the template dilution in the correcting PCR to the levels recommended by the enzyme's manufacturer and therefore to include a template removal step before transformation.
Such analyses, however, will be limited by the correct calculation of the color variables.
The present method provides convergent and reasonable results for a full range of variations in fiber section shapes (from circular fibers to ribbons), for a complete spectrum of the fiber volume fraction (from 0 to 1, and the latter limit shows the correct asymptotic behavior in the fully packed case) and for extreme types of the inclusion phases (from voids to rigid inclusions).
For example, the frequentist-based 95% confidence interval is often interpreted as meaning that there is a 95% chance that a parameter of interest lies between an upper and lower limit, whereas the correct interpretation is that 95 of 100 replications of exactly the same experiment capture the fixed but unknown parameter, assuming the alternative hypothesis about that parameter is true.
The waiting for the correct tRNA limits the elongation process [10], [11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com