Sentence examples for limit side effects from inspiring English sources
These findings expand the knowledge base on normal tissue responses and may help to evaluate and limit side effects of radionuclide therapy.
Some analogs also showed high selectivity against other CYP enzymes such as 3A4, 1A2, 2C9, 2C19 and 2D6, which may limit side effects due to drug-drug interactions.
It is likely that inducible promoters will be required in the future to limit side effects (see below) and yield penalty. Finding such specific promoters is one of the major challenges in this field, and current experiments on whole transcriptome analysis under different biotic and abiotic stresses will provide numerous candidate promoters for cloning.
Compound 14d displayed the best in vitro pharmacological profile with full PPARγ agonist activity (Emax = 98%, EC50 = 200 nM), SIRT1 enzymatic activation (+128%) and SGK1 expression inhibition (- 57%) which is known to limit side effects as fluid retention and body-weight gain.
Regarding the risk of oncogenesis, it has been previously proposed that one must consider, as for any toxicology study, cell dose with the hypothesis being that limiting cell dose will limit side effects [10].
The receptor is therefore a possible target for drug intervention because of the potential to limit side effects.
Targeting MIF under these circumstances might alter the tumors' capability of withstanding radiation or chemotherapy, thereby increasing effectiveness and limiting side effects.
4030W92, at 25 mg/day, produced a nonsignificant reduction in pain without treatment limiting side effects.
Since the beginning of the use of high-dose pulses of corticosteroid, there was anticipation that there would be significant and limiting side effects.
Recent developments have demonstrated how vector gene expression may be regulated and further improvements to vector design have limited side effects and improved safety profiles.
This provides an excellent framework to aid in the design of novel antipsychotics with diminished propensity to produce clinically limiting side effects.
