(Additional File 2) There is no general consensus on the exact limits of moderate consumption or binge drinking and various cut off points as grams of alcohol [ 17] or qualitatative characteristics of drinking occasions [ 18] have been suggested.
Research into heavy drinking is compromised when alcohol consumption of the majority of respondents falls within the limits of moderate drinking [ 23] in populations with traditionally irregular drinking patterns [ 24].
43 The lower limits of moderate and heavy infections were 5,000 and 50,000 EPG for A. lumbricoides, 1,000 and 10,000 EPG for T. trichiura, 2,000 and 4,000 EPG for hookworm, and 99 and 399 EPG for S. mansoni, respectively.
Scores of 5, 10, 15 and 20 represent thresholds marking the lower limits of mild, moderate, moderately severe and severe depression.
The risk score for the virus's potential to impact public health if it were to achieve sustained human-to-human transmission is 7.0, which falls in the upper limit of the moderate-risk range and which is higher than the preliminary score of ≈6.0 in mid-April.
To better handle irregular boundaries and keep the computation cost well in a reasonable limit, unstructured grids of moderate scale are used.
The expression of the reaction rate in the limits of small, moderate and large L/H values were obtained by scale analysis.
Dosing should be withheld in patients with grade 2 hepatic toxicity, defined as moderate alanine or aspartate aminotranferase elevations of >2.5 5.0 times the upper limit of normal, or moderate total bilirubin elevation of >1.5 3.0 times the upper limit of normal.
Unfortunately, methods based on Lander Green algorithms are limited to pedigrees of moderate size since the running time grows exponentially with pedigree size.
Even though the sequences are limited to moderate values of i, there would not be enough data to estimate reliably all of the conditional probabilities.
