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The simulations indicate that the process approaches the steady-state, Zipf's law-like distribution regardless of the initial state distribution when model parameters are set to the typical value of mammalian cells (M = 300,000, N = 20,000), and the lower limit of expression level L is set to 1.0 [copy/cell] (Figure 1C).
In the foot of both chicken and alligator, late HoxD-11 expression is slightly more shifted towards posterior: The anterior limit of expression is found along the posterior border of digit 2 (white arrows in hind limb stages 17 18 of the alligator, black arrows for stages 30 and 34 of the chicken hind limb).
Upregulation of these genes might not exceed a certain limit of expression because protein concentration will quickly increase in the small intracellular compartment, where they act.
For mespa we used a grid to measure the distance between the posterior tip of the embryo and the posterior limit of expression.
Its anterior limit of expression is more graded and less well defined and ectopic anterior margin in the adult wing can only rarely be observed.
According to the threshold model, all birds have migratory activity, although in residents this is below a limit of expression or detection.
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The result is not just a great book, but a valuable document of the limits of expression in the mid-sixties U.S.S.R. Reading though the text in bold, some of the censors' cuts come as no surprise: "I hope Stalin croaks!," Kuznetsov's grandfather says on page 62.
By September, his problem had made its way into the liberal Copenhagen daily Politiken, and was promptly co-opted by the conservative daily Jyllands-Posten, whose arts editor — now on "indefinite leave" — asked forty artists to "test the limits of expression" by drawing pictures of Muhammad.
As described above, the CZ and NZ are delineated by the limits of expression of the Purkinje cell stripe marker HSP25 [31].
Consequently, their ventral limits of expression are determined by Shh signalling.
The noise (or limits) of expression detection in the mRNA-seq data is the peak of the distribution of expression values (genes with high expression are in the long tail of this distribution).
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CEO of Professional Science Editing for Scientists @ prosciediting.com