limit of determination

USAGE SUMMARY

The phrase "limit of determination" is correct and usable in written English.
It can be used in contexts related to scientific measurements, analytical chemistry, or any field where a threshold for detection or quantification is discussed. Example: "The limit of determination for this assay is crucial for ensuring accurate results in our experiments."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

44 human-written examples

The limit of determination in NL values (LODNL) for the sensor bacteria was determined in every assay as follows: (2) where is the mean background luminescence value of the sensor (minimum six blanks included in each assay) and SD is the standard deviation.

BMC Biotechnology

The limit of determination was 0.034 μmol l−1 which shows high sensitivity of the developed method.

Electrochimica Acta

A limit of determination of 0.5 nM and a sensitivity of 0.011 μA nM−1 was obtained.

Electrochimica Acta

Common degradation products such as HMF, furfural, or acetic acids which can also be quantified by the application of the HPLC method were either not detected or below the limit of determination.

Bioresources and Bioprocessing

Samples with perchlorate values below the elaborated limit of determination of 0.33 µg/L were chosen and spiked with perchlorate to achieve a nominal concentration of 1.5 µg/L (RL).

Environmental Sciences Europe

It was shown that the creatinine-sensitive biosensor, created by covalent cross-linking in GA vapor, was threefold less sensitive to creatinine and had three- to fourfold longer response time and twice the minimum limit of determination.

Nanoscale Research Letters

Human-verified similar examples from authoritative sources

Similar Expressions

16 human-written examples

The limits of determination and quantification were found to be 0.08 and 0.27 mg l−1, respectively.

Analytica Chimica Acta

The limits of determination and quantification of SYP were estimated to be 0.78 μg/g and 2.60 μg/g of food sample, respectively.

Food Chemistry

Quantification through internal standard calibration resulted in low limits of determination (DEHP 4 mg kg− 1 to DBP 14 mg kg− 1).

Environment International

Under these conditions, linear calibration curves were obtained over the range of 0.01 8.00, 0.01 10.00 and 0.01 3.00 μg/ml for VB1, VB2 and VB6 with the limits of determination of 0.008, 0.005 and 0.006 μg/ml, respectively.

Analytica Chimica Acta

These stochastic sensors were used reliable for both qualitative and quantitative analysis for the assay of glycogen in tissue samples with limits of determination as low as 1 fmol L−1.

Journal of Pharmaceutical and Biomedical Analysis

Expert writing Tips

Best practice

When reporting analytical results, clearly state the "limit of determination" to provide context for the reliability of your measurements. This ensures transparency and helps others interpret your data accurately.

Common error

Avoid using "limit of determination" interchangeably with "limit of detection". The "limit of detection" refers to the lowest level at which a substance can be reliably detected, while the "limit of determination" refers to the lowest level at which a substance can be quantified with acceptable accuracy and precision.

Linguistic Context

The phrase "limit of determination" functions as a noun phrase that specifies the lowest concentration of a substance that can be reliably measured and quantified. Ludwig AI confirms its use in scientific contexts, as shown in the examples.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Wiki

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Ludwig's WRAP-UP

The phrase "limit of determination" is a crucial term in analytical chemistry and related fields, representing the lowest concentration of a substance that can be reliably measured and quantified. As Ludwig AI confirms, it's grammatically correct and most frequently used in scientific contexts. It is important not to confuse it with the "limit of detection", which only indicates the lowest detectable level. Alternatives include "quantification limit" and "minimum quantifiable level". When reporting analytical results, always clearly state the "limit of determination" to provide context for the reliability of your measurements.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

detection limit

Focuses specifically on the point at which something can be detected, not necessarily quantified.

quantification limit

Highlights the point at which a measurement can be reliably quantified.

limit of quantitation

Alternative terminology referring to the point at which reliable quantification is achieved.

minimum detectable level

Emphasizes the lowest level at which a substance can be detected.

lowest limit of detection

Specifies the absolute lowest point at which detection is possible.

threshold of detection

Implies a clear boundary where detection begins.

sensitivity threshold

Highlights the sensitivity of a method in detecting a substance.

minimum quantifiable concentration

Specifically refers to the lowest concentration that can be measured.

assay sensitivity

Focuses on the sensitivity of an assay in determining a substance.

lower detection bound

Indicates the lower boundary for reliable detection.

FAQs

How is the "limit of determination" calculated?

The "limit of determination" is typically calculated based on the standard deviation of blank samples or the calibration curve. A common method involves multiplying the standard deviation of the blank by a factor, often 10, to ensure reliable quantification.

What's the difference between "limit of detection" and "limit of determination"?

The "limit of detection" is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value). The "limit of determination", also known as the limit of quantification, is the lowest quantity that can be measured with reasonable accuracy and precision.

Why is knowing the "limit of determination" important in analytical chemistry?

Knowing the "limit of determination" is crucial because it defines the range within which quantitative results are reliable. Measurements below this limit are considered unreliable for quantitative analysis, ensuring data integrity and validity.

What are some alternative phrases for "limit of determination"?

You can use alternative phrases like "quantification limit", "minimum quantifiable level", or "lowest level of quantification" to convey a similar meaning.