However, short-term cultures limit insight with physiological relevance because the cells and tissues have not reached a steady-state.
The author discusses neuroscience research that shows how mental models, such as those implicit in specific disciplines, shape and limit insight and action.
This lack of insight hinders our ability to fully understand the molecular basis of the therapeutic and adverse effects associated with a major class of anticancer agents and may limit insight into a fundamental cause of age-related disorders.
Hospitality management graduates have limited insights into latest operational/technological concepts such as Industrial Cuisine, Molecular Gastronomy and Personalised Nutrition.
As a result of poor sequence homology between MAGL and chloroperoxidase, the homology model offered limited insights into the overall structure and organization of MAGL protein.
Their drawback is the singular nature of measurements at only one time point, which limits insights into the scope of a response and leaves doubt whether the best time point had been selected for data collection.
However, this research has been based on a small number of participants, primarily with sexual or reproductive cancers, which limits insights into the experience of individuals with other types of cancer.
Although IBD is believed to result from an inappropriate inflammatory response to commensal microbes in a genetically susceptible host, we only have limited insights into its pathogenesis, underlining the importance of finding novel genes and pathways that might contribute to the inflammatory process.
DOI: http://dx.doi.org/10.7554/eLife.07113.001 Quantitative analysis of transport activity in vivo is extremely challenging, and popular methods, such as crystallography, patch clamping and radioactivity assays can only give limited insights since they are often destructive or are restricted to cell surface studies.
Beyond the significant correlation between increasing intestinal length and decreasing animal prey in diet, interpretation of the evolution of specific dietary habits in the Terapontidae must be treated with caution as we currently have limited insights into the physiological processes associated with extracting and utilizing nutrients from consumed foods.
