Short-term exposures to topotecan were used in order to limit the cohort of cells undergoing DNA replication during drug exposure and to limit the confounding effects of pH-dependent topotecan inactivation (Chourpa et al, 1998).
Combining with family-based case-control design may be a viable option to limit the confounding effects of environmental risk factors in neuroimaging studies of schizophrenia.
In order to limit potential confounding effects of other conditions affecting immunity, patients with one or more severe comorbidities (i.e., the human immunodeficiency syndrome, hematologic malignancies evolving from insulin-dependent diabetes, the dialyzed chronic renal failure, chronic liver disease stages III and more) or patients receiving immunosuppressive therapy were excluded.
In all cases, cultures were maintained in the presence of saturating concentrations of exogenous EGF in order to limit any confounding effects from autocrine/juxtacrine EGFR activation [13].
To limit any confounding effects of ontogeny on comparative analyses in the present study, assessment focused on the morphologies and dietary habits of the largest size classes only (i.e., when intestinal length was most fully developed).
In addition, in order to limit the confounding effects of multiple comorbidities and the exposure of frail individuals to an inactive placebo treatment, this study recruited outpatients who met a set of entry criteria comparable to those typically found in clinical trials of anti-dementia therapies, but which may not be fully representative of an actual out-of-trial population.
Using available whole-genome sequence data and a suite of tools developed to limit the confounding effects of errors associated with draft genomes, we decompose the P. syringae pan genome into its constituent core and flexible components and apply various phylogenomic methods to infer the evolutionary histories of both these entities.
The HADS was chosen because the scale is designed to measure the presence and severity of depressive and anxiety symptoms whilst limiting any confounding effects of physical illness symptoms by excluding somatic items.
Selection of an appropriate reference group has been suggested elsewhere [ 5, 12] assuming that workers in other rather similar industries may both be subject to the same selection in and out of occupation and may, furthermore, be rather similar in respect to education and income, thereby limiting the confounding effects of social factors.
To limit the confounding effect of homeostatic proliferation, we performed an analogous experiment in a GvH model.
