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This small genome size was chosen to limit computing time.
Therefore, we anticipate moving to a Bayesian method to take advantage of whole-genome sequence data and increase prediction accuracies, and we expect that an EM algorithm will be part of this methodology in order to limit computing time.
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The limit on computing time with parallel CCH is simply a product of the number of available cluster nodes.
Metascape's architecture is designed to support a seamless user experience towards the analysis and visualization of an arbitrary number of gene lists, only limited by available computing time and memory space.
Obviously, while this complexity and required computing time might limit application of the I/C model, potential gains in efficiencies are likely in the future.
To decrease the complexity of the RepeatScout output, limit false positives, and minimize computing time, we devised several filtering steps to apply to RepeatScout output prior to running REPCLASS.
The number of rearrangements per addition sequence replicate in bootstrapping was limited to 10 to save computing time.
Furthermore, standard methods of FDR calculation using decoy databases derived from search databases of this size are increasingly impractical, notably as the computing time is limiting.
For applications for which computing time is limiting, DAGPHASE using information from Beagle can be considered as an alternative, since it reduces computation time and increases imputation error rates only slightly.
Various techniques have been applied in the simulation of hydraulically fractured wells using finite difference simulators; most of these techniques are limited by the grid dimensions and computing time and hardware restrictions.
Application of DAGPHASE using information from Beagle gave slightly poorer results but is an interesting alternative in applications where computing time is a limiting factor.
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CEO of Professional Science Editing for Scientists @ prosciediting.com