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For CTL* more axioms must be added, to account for the combinations of temporal operators and to enforce the limit closure property.
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The PCM-FPI response looks better, close to the one brought by the hybrid models, especially when using a Bi-Modal-Limit closure of scalar dissipation rate.
Together, these data support a model in which the N-terminal strap limits closure by inhibiting the rotational movement of the NTD that is necessary to form the catalytically active closed state.
These two limiting closures are then used to build a general algebraic closure of the mean dissipation of reactive scalar fluctuations.
We threw everything we had into a campaign to get the government to limit the closure, if not to stop it.
The Lautaret pass is defined by the General Council of the Hautes-Alpes region (Tacnet et al. 2013) as the main economic link, and constant pressure is exerted by local decision-makers and tourism professionals to limit its closure.
12 However, these guidelines did not propose a time limit for closure.
Indeed, when powders of silica nanoparticle rather than solutions were spread, the particle agglomerates limit wound closure and healing (Supporting Information, Figure S2).
DOI: http://dx.doi.org/10.7554/eLife.03487.018 While the crystal structure of the TRAP1 closed state revealed that the strap made stabilizing interactions with the trans protomer, we show here that its dominant role in modulating ATPase activity is to limit the closure kinetics, presumably though analogous cis-protomer interactions in the apo state.
Displacement of cis-protomer contacts from the apo state is rate-limiting for closure and ATP hydrolysis.
It was supposed that without ILM peeling, the remaining vitreous may act as a scaffold for the epiretinal membrane, thereby exerting traction on both the MH and retina in the posterior pole, thus limiting MH closure or even promoting reopening.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com