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This classical approach assumes that absorption, distribution, metabolism, and excretion processes are first order, but does not always take into account potential saturation clearance limitations for some chemicals, or that blood flow can limit clearance.
The critical value of the clearance is called the lower limit clearance.
Therefore a practical slider air bearing should be designed so that the clearance at operation is always greater than the lower limit clearance with a safe margin.
The lower limit clearance is general of several nm in magnitude, and increases as the ratio of hmax/hmin and/or the slope of the slider decreases.
Similar(56)
"What have they been doing for the last eight years?" The second-floor balcony has limited clearance between the railing and the ceiling of the stairwell from which it looks out.
17 APOC3 is transported on circulating lipoproteins and limits clearance of TG-rich particles.
Intense exposures in early years and some jobs (mill sweeper, railroad car cleaner) may have resulted in overload, limiting clearance even of small fibers (ATSDR 2003).
But as a defense industry consultant, Mr. Deutch retained limited clearances, Mr. Cohen said.
Traditionally, to limit NP clearance by the RES system, the NP surface is neutralized with molecules like poly ethylene glycol) (PEG) which are known to resist protein adsorption and RES clearance.
The N-linked polysaccharide side chains appear to be important for the biosynthesis and secretion of EPO, enhance its stability in blood, and limit hepatic clearance, thus facilitating the systemic transit of EPO from kidney to bone marrow [2].
In addition, the capillary network around fast fibers is less developed, which should limit lactate clearance [ 64, 73].
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CEO of Professional Science Editing for Scientists @ prosciediting.com