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Importantly, the compression process can be controlled and customized to limit cell damage.
However, in recent years, it is being increasingly recognized that, in individual cells, there are graded responses collectively termed cell-autonomous defense mechanisms that induce cellular processes designed to limit cell damage, enable repair, and eliminate bacteria.
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ALDHbr cells were purified from the atrial population, which was enriched for these cells compared to ventricles, in order to abbreviate the FACS procedure, thereby limiting cell damage.
Such pan-caspase inhibitors would be ideally suited to be effective as interventions for the acute posttraumatic inflammation and to limit cell and cartilage damage.
Interestingly, mechanistic analysis of cancer cell lines has shown that direct targeting of Rb by miR-335 also establishes a proximal connection to the p53-dependent stress response since, by altering the Rb levels, miR-335 activates the p53 pathway to limit cell proliferation after DNA damage [ 106].
A cancer occurs when something causes a mutation in the genes that limit cell growth or that repair DNA damage.
Our bodies use antioxidants to limit the cell damage (called oxidative stress) that occurs, for example, when you're digesting food, or exposed to smoke.
We conclude that addition of testicular hyaluronidase to storage UW solution limits liver cell damage and considerably improves graft function.
Indeed, during HIV and influenza infections, IL-22 limits epithelial cell damage at mucosal surfaces (Kim et al., 2012; Kumar et al., 2013).
Up-regulation has been shown in individual GSTs during pathogen attack in numerous plant species (e.g. Mauch and Dudler 1993; Alvarez et al. 1998), with likely involvement in detoxification of products of oxidative stress during HR, thus limiting both cell damage and the extent of cell death.
Telomere shortening is a cell-intrinsic mechanism that limits cell proliferation by induction of DNA damage responses resulting either in apoptosis or cellular senescence.
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