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From the structural and lithological point of view, stock-like, well zoned pegmatites, e.g. Hagendorf-South, developed in the hinge zone, whereas tabular aplites, such as Reinhardsrieth, evolved along the limb zone of strongly folded basement rocks.
Average porosity values of 8%to10%0% were assumed In sector 4, water saturation varies from 45% in the southern flank to 90% in the northern limb The NTG ratio is about 95% in the southern flank decreasing to 50% in the northern limb Zone 8 Thickness 72 m and composed of shale, marl and marly limestone Porosity of 9%10%% was estimated.
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Areas with well-developed tectonic fractures are mainly controlled by the tectonic stress field and elastic strain energy density, typically located in the fold limbs, fault zones and locations of changes in the orientation of fault.
One of the Hh ligands, Sonic hedgehog (Shh), is secreted from the posterior mesenchymal region of limb buds, the zone of polarizing activity.
Both fins and limbs have a zone of polarizing activity (ZPA), a specialized population of mesenchymal cells at the posterior edge of the bud that controls anteroposterior patterning via secretion of the Sonic hedgehog (Shh) protein [21] [23].
We did not observe, for example, isolated cells or patches of cells that were either Ihh- or Col10a1-positive within the proliferative zone of limb bones.
Further analysis revealed a required role for SHP-2 in mesenchyme of the progress zone in limb buds.
The AP axis is controlled by a small region in the posterior limb bud called the zone of polarizing activity (ZPA).
SHH is a morphogen that is produced in a single, restricted domain lying at the posterior margin of the developing limb bud called the zone of polarising activity (ZPA).
The signalling molecule Sonic Hedgehog (Shh) is normally expressed in a spatially and temporally restricted fashion in the posterior part of the developing limb bud, termed the zone of polarizing activity (ZPA).
Shh initiation and spatial expression control within the posterior margin of the limb bud called the zone of polarizing activity (ZPA) is also regulated by a cis-regulatory element designated the ZRS (Lettice et al., 2002, 2003; Sagai et al., 2004, 2009).
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