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Likewise increased expression of glycolytic enzymes supports the survival and growth of tumour cells under hypoxic conditions (Malhotra and Brosius, 1999).
Likewise, increased expression of prostaglandin-endoperoxide synthase 2 (PTGS2) leads to increased production of PGE2, which promotes cancer cell growth through EP2 receptor-mediated signalling (Castellone et al, 2005).
Likewise, increased expression of IFN-γ and predominance of Th1 response are observed in human SLE and further in another lupus-prone NZB/W mice [ 27, 41], and exacerbation of SLE and lupus-like syndrome in myeloproliferative disease was induced by treatment with IFN-γ [ 42, 43].
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Likewise, we confirmed the increased expression of GRP94 in colorectal cancer tissue and the significant down-regulation of the IgGFcBP expression in tumour cells.
Likewise, NK cells display increased expression of activating receptors such as NKp30, NKp46, and NKG2C with decreased expression of the inhibitory marker NKG2A.
Increased expression of adiponectin was also detected.
Likewise, COX-2low melanomas showed a qualitative change in infiltrate composition, displaying increased expression of anti-tumor mediators and hallmarks of activation of the type I IFN system.
It is likewise noteworthy that the liver primed activated CD8+ T cells have diminished expression of CD25 and increased expression of CD62L.
Likewise, when parental WPMY-1 cells were transfected with an androgen responsive reporter vector, they showed no evidence of increased expression of the reporter (luciferase) in response to increasing amounts of DHT (Fig. 1C).
Increased expression of miR-200c-3p miR-200c-3p miR-200c-3protein expression.
Paradoxically, there was increased expression of DNAJC3.
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