Woodruff also sees theater as essential to the human spirit, and his book likewise functions as a defense, but he faces a problem Aristotle did not, and thus his defense must be effective on two fronts: first, against Plato (as well as Rousseau, Brecht and others who saw theater as being potentially destructive of a healthy society); second, against apathy.
Several studies have likewise suggested that MCPH1 may also function as a tumor suppressor [ 3, 23].
This could also function as a bypass.
Likewise, RNase L also functions as a splicing factor and a RNA-level regulator of the unfolded protein response in eukaryotes [ 20, 31].
Likewise, H19 can function as a primary microRNA precursor [ 122] and H19-derived miR-675 increases cell proliferation in gastric cancer cells by targeting the tumor suppressor RUNX1 [ 123].
Likewise, γ-catenin also functions as both a transcriptional effector of canonical Wnt signaling and as a junctional component (Zhurinsky et al. 2000; Maeda et al. 2004; Shimizu et al. 2008).
Likewise, the plexD1 agonist sema3E was found to inhibit the invasion of blood vessels into somites during embryonic development [9] suggesting that sema3E too may function as an anti-angiogenic agent.
Likewise, KLHL20 was also reported to function as an E3 ligase in combination with Cullin3 on death-associated protein kinase (Lee et al., 2010), PDZ-Rho guanine nucleotide exchange factor (Lin et al., 2011) and promyelocytic leukemia protein (Yuan et al., 2011).
Likewise, VP16's capacity to function as a transactivator of IE genes has been considered as a potential target of differential regulation [64], [65], [66].
Likewise, centromere function as monitored by the loss rate of a centromere plasmid was increased in rrm3Δ but not pif1Δ cells, and was even higher in rrm3Δ pif1Δ cells than in rrm3Δ cells.
