Results of Table 4 revealed that quinazoline 2 obeyed the Lipinski rule of five in drug-likeness test [51].
GO-Y030, FLLL-11, and FLLL-12 pass the drug-likeness test, with FLLL-12 having the highest drug-likeness.
To address this issue, we conducted lexical decision and symbol detection tasks using stimuli that varied parametrically in their word-likeness, and tested for task by stimulus class interactions.
To test kinase-likeness of the compounds that are frequently used in virtual screening of kinase inhibitors, the following publicly available small-molecule databases were also collected: the National Cancer Institute database (NCI), the Natural Products database (NPD), the National Institute of Health's Molecular Libraries Small Molecule Repository (MLSMR).
Absorption, Distribution, Metabolism, Excretion and Toxicity (ADME/Tox) are main five parameters to test the drug likeness of a molecule.
To determine the kinase-likeness of any given database (test database) of compounds, we randomly chose 1% of the known kinase compounds from the KBD and seeded them into the NCI, NPD, MLMSR, and WDI databases.
Sperm banks and egg vendors offer online ordering and direct shipping of donor materials that prospective parents can shop for based on SAT scores, personality tests, even celebrity likeness.
A similar approach has already been applied by Ohno et al. to rank order various test databases for drug-likeness [56].
A third is that precise mathematical results on GRFs can be used for testing how close this likeness is, and to make the relationship between GRFs and mature V1 maps clearer.
Sylvia Anderson was to bring the character of Lady Penelope to life in both likeness and voice: after a number of test models were rejected, sculptor Mary Turner decided to use Anderson herself as the template for the character.
In the post-session ratings (Supplementary Table 2), the SRH correlated positively across subjects with estimates of speech-likeness (versus thought-likeness; r = 0.54, P = 0.04; Pearson's one-tailed test) and loudness (r = 0.52, P = 0.05) of the hallucinations, as well as with hallucination-related suffering (r = 0.59, P = 0.03).
