Biomarkers that identify patients more likely to develop severe disease should expedite successful development of disease-modifying OA drugs and improvements in medical and surgical management of knee OA.
Jhp0945-positive isolates may be more likely to develop severe diseases, and jhp0945 status may be a risk indicator for GC development.
Patients with the DRB1*1501/DQB1*0602 haplotype mounted significantly reduced responses and were less likely to develop severe systemic disease (P < 0.0001).
Dr. Fry and his co-investigators found, for example, that patients with malnutrition or kidney failure were more likely to develop severe wound infections after heart bypass operations.
Catch one strain and you will be immune to the virus in future – but if bitten by a mosquito carrying another of the strains, you are more likely to develop severe dengue, also known as dengue haemorrhagic fever.
Some research has suggested that people with big bellies are more likely to develop severe knee OA and require joint-replacement surgery, so an international team of arthritis experts decided to investigate whether the location of body fat influences risk.
African Americans, for example, are less likely to develop severe degrees of ROP.
It therefore appears that msp2 genotypes are associated with asymptomatic carriage and that children with mono-infections are more likely to develop severe malaria than children with polyinfection.
Because individuals with a history of alcohol abuse are more likely to develop severe pneumonia leading to ICU admission, the effect of chronic alcohol exposure on immunity of the lung has been assessed in many in vitro and in vivo studies [10, 12].
After adjusting for factors such as socioeconomic status and the use of other drugs, the researchers found that among young adults with a predisposition for mental illness, those who smoked pot were more likely to develop severe psychosis than those who abstained.
Early trials for sepsis showed that the drug reduced the death rate after 28 days and patients were less likely to develop severe respiratory problems.
