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This comparison is not likely to be invalidated by the lack of information on mutation status in the controls since so few positive controls were expected.
Unfortunately, the key underlying assumption that a fine-mapping locus contains a single causal variant is likely to be invalidated at many risk loci (Hormozdiari et al., 2014; Kichaev et al., 2014).
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Generally speaking, the more conservative the member the more likely they were to believe that more would have to be invalidated.
There were calls for a recount, or even for the election to be invalidated.
It's vulnerable to being invalidated through the courts.
If the state of Texas loses the lawsuit, the temporary license issued to Karnes would likely be invalidated.
If the experiments are performed in different laboratories and at different times, the experimental designs are likely to be different enough to invalidate or at the least complicate the analysis.
If you remain in the country your travel insurance will likely be invalidated, unless you can prove you have made a concerted effort to leave the country.
2) Duress - If one party is pressured into signing the agreement or had no mental capacity to sign the agreement (such as been drunken or under the influence of drugs), the agreement will likely be invalidated by the Court if challenged.
The big fight is likely to be over expanding the Covered Business Method program to invalidate low-quality patents.
Thus, the presence of random error will increase the probability of a type II statistical error (failing to detect significant associations) but does not invalidate a statistically significant result; we therefore believe that our findings are likely to be correct.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com