Tolstoy here only wants to capture the mystery of that generalising, transcendent yearning and then correct, as the story unfolds, for its likely interactions with the real.
Instead, we did find a family of solutions much simpler than the original superstructure containing all likely interactions, with a very good fit to the experimental data.
Their low intrinsic stability in the lipid-free state likely facilitates interaction with lipid surfaces.
These results demonstrate that DnaK is required for quality control of CsgA as well as CsgB, likely through interaction with aggregation-related signal peptides.
These large fold reductions in affinity suggest that contribution of D292 extends beyond its likely electrostatic interaction with Lys4 in H3 and into structural organization of the N-terminus of the PHD1 for histone binding.
Furthermore, it is likely that interaction with IP3 receptors and several subsequent signaling molecules are involved in the mechanism underlying the pharmacological action of sigma-1 receptor agonists.
Indeed, lack of HIPK2 nuclear accumulation during hypoxia, as seen in Figure 5B, and likely of interaction with other proteins, can mechanistically explain inhibition of HIPK2 co-repressor function on DNA, nonetheless HIPK2 keeps its kinase activity.
However, the nucleolus is not surrounded by an additional membrane and the localization to this subnuclear domain likely requires interaction with other components in the nucleus or the nucleolus [31], [32], [33].
As striatum activation was related to both suppression of M1 and anticipation of a stop-signal occurring, these findings suggest that the striatum is involved in proactive inhibitory control over M1, most likely in interaction with SMC and rIFC.
Majority of Mdj1 localizes to the nucleoid, likely via interaction with mtDNA.
