Sentence examples for likelihood of mutations from inspiring English sources

The amplification of the whole F′ lac plasmid suggests that directed mutation may mean increased likelihood of mutations on this plasmid due to repeated replication and copy-number increase and not to mutagenesis.

Or do the new copies of the RNA also get copied themselves in a 'geometric replication mode' that increases the likelihood of mutations and enables the virus to evolve more rapidly?

By increasing the likelihood of mutations and facilitating malignant cellular adaptation, and thus enabling premalignant cells to reach the essential hallmarks of cancer (Sherman and Multhoff, 2007), HSF1 may contribute to oncogenesis.

This is not surprising, because the codon ends with dinucleotide TA, which is known to be suppressed in the coding sequences of several plant species possibly to discourage insertion events that target the TA dinucleotide, to reduce the likelihood of mutations leading to stop codons and to prevent attacks by TA-specific RNases.

That is, once a stem cell is formed, one of its DNA strands remains selectively segregated into a stem cell during division (as part of self renewal of that cell), reducing the likelihood of mutations accumulating in the stem cells during subsequent DNA replication.

Compared to more traditional types of plant mutation techniques, using x-rays or gamma rays, plants need to be exposed to only a low dosage of powerful heavy ion beams for a short time — seconds and minutes instead of hours, days or weeks — for a high likelihood of mutation to occur.

If mutations to single drugs occur early during the within-host expansion of a population so that mono-resistant bacilli constitute a major portion of the bacterial population at the time of detection, the likelihood of mutation resulting in resistance to a second drug during the subsequent growth of the population is increased.

Country-stratified estimates of the likelihood of mutation status by histopathological markers were derived using a Mantel-Haenszel approach.

At least one ovarian cancer in a high-risk family increases twice the likelihood of mutation detection.

Inflammation leads to genotoxic events as well as cellular proliferation and tissue remodeling, which are processes that increase the likelihood of mutation and progression towards neoplastic lesions.

In this hypothesis, it is speculated that the increased stimulation of cell growth in allergy and chronic inflammation increases the likelihood of mutation of dividing stem cells and malignant proliferation.