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However, the likelihood of benefiting from experimental treatment was similar between different PS groups.
Most importantly, these results allow for much better estimates of an individual patient's likelihood of benefiting from intervention (fig 2).
While higher risk patients have a greater likelihood of benefiting from systemic therapy, in our view, treatment stratification based on prognostic biomarkers is not the ultimate goal.
The translation of the intrinsic subtypes of breast cancer into clinical assays may enable us to stratify patients by their likelihood of benefiting from adjuvant treatment.
If confirmed by prospective studies, these data suggest the possibility that such SNP analysis could be used to identify patients with an increased likelihood of benefiting from this rationally designed regimen.
Epidermal growth factor receptor (EGFR) gene mutations identify patients with non-small cell lung cancer (NSCLC) who have a high likelihood of benefiting from treatment with anti-EGFR tyrosine kinase inhibitors.
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The aim of the study is to analyze the relationship between the severity of 25OH deficiency at ICU admission, severity of illness and outcomes and ultimately to identify subgroups of patients in whom the likelihood of benefit of supplementation is larger.
The purpose of this is to show how the NNT can help clinicians to converse with patients to convey details about the likelihood of benefit with treatment and/or the likelihood of risk, in order that a decision may be made with respect to therapy.
Preliminary data also suggest that directed nodal radiation therapy to the supraclavicular and internal mammary lymph nodes may prove beneficial; publication of several studies are awaited to confirm these results and to help define subgroups with the greatest likelihood of benefit.
The improved likelihood of benefit was seen in all subgroups.
We specifically identified the ways in which practitioners framed the likelihood of benefit.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com