Exact(5)
Like virulence studies, the laboratory assessment of brucellosis vaccines has been almost always based on experiments in mice, and there is a useful mouse model for the evaluation of S19 and Rev 1 vaccine stocks.
Examples of public goods are exoproducts like virulence factors damaging the host, enzymes for the digestion of food sources, surfactants for facilitating movement, and nutrient scavenging molecules such as siderophores.
The spatiotemporal regulation of intracellular cyclic-di-GMP is central to many important cellular processes like virulence, biofilm formation, quorum sensing, motility, and cell division.
Beside several probes in categories like virulence, extracellular (secreted proteins) or transcription, the probe set comprises a relatively large fraction of probes originating from intergenic regions.
On a semantic note, in efforts to promote studies of beneficial microbe/animal associations as informing parasitic or pathogenic associations, Margaret McFall-Ngai has suggested that terms like "virulence" and other disease related terminology be changed to more neutral terms, which I heartily endorse.
Similar(55)
For their ubiquity in bacterial pathogenesis, these lectin-like virulence proteins have been drug targets and vaccine components.
Specialized Sec-independent transport systems like that initially identified in Mycobacterium tuberculosis responsible for exporting ESAT-6-like virulence factors have been found in a variety of low G+C Gram-positive bacteria including Bacillus anthracis, Staphylococcus aureus, and Streptococcus gordonii [54].
NLPs have been suggested to have dual functions in plant pathogen interactions: acting both as triggers of defense responses and as toxin-like virulence factors.
This set of genes could contain virulence genes acquired by 99-738 DP-B5 that endow it with clade 2-like virulence.
Conversely B. cereus strains that have acquired the known B. anthracis mega-plasmids and anthrax-like virulence properties remain an enigma and are also worthy of further study to understand how this pathogen interacts with its host [ 12- 14].
Several results suggest that P. parasitica may produce a toxin-like virulence factor similar to necrosis and ET-inducing peptides characterized in other fungal pathogens such as Phytophthora spp. [ 39], Botrytis spp. [ 40] and Pythium aphanidermatum, during compatible-necrotrophic interactions.
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