Exact(1)
A third possibility is that the lesions associated with casting-type calcifications histologically initially exhibit features of in situ carcinomas even when recurring, but in reality they behave like invasive tumours by ductneogenesis (Tabár et al, 2007).
Similar(7)
These data suggest that BCL9 may predispose to the development of basal-like invasive breast cancers.
Basal-like invasive breast cancer is associated with a worse prognosis.
We observed that beta1-integrin and/or PI3K pathways differentially regulate early vs. late stromal matrix induced (in vivo-like) invasive behavior.
The effects of downregulation of TFPI were investigated in the two basal-like invasive breast carcinoma cell types Sum102 and MDA-MB-231.
Interestingly, these cells co-express keratin and vimentin consistent with an EMT (epithelial-mesenchymal transition -like invasive phenotransition -likeother cancer stem cell characterinvasiveWilliphenotypeaselfeldt et al, 2005; Bartkowell et as, 2009; Jother et al, 2012).
Indeed, alleviation of this nutrient stress condition by exogenously provided L-Pro induces proliferation and modifies the ESC phenotypic and molecular identity towards that of mesenchymal-like, invasive pluripotent stem cells.
These characteristics are associated with stem-like, invasive, and aggressive aspects of breast cancer, and suggest that inhibiting GLI1 may be an effective treatment strategy for patients with claudin-low breast cancer.
Related(1)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com