Characteristic cytoplasmic stippling and coarse granularity was present in all cases including compact cytoplasmic "Leishmaniasis-like" globules.
Using a mesoscale computer simulation, we show that the protein-like globules can have a large number of catalytic centers located at the hydrophobic core/hydrophilic shell interface.
Characteristic features of a cylindroma include monomorphous appearing basaloid islands, eosinophilic hyaline-like globules, thickened eosinophilic basement membrane surrounding the lobules and a jigsaw puzzle-like pattern of growth.
In all cases we observed very pronounced transitions from the extended coil conformation to the pearl necklace-like globule with an increase of salt concentration.
It was a white, gauzy scrim that stretched into shapes suggesting the inside of a body, with tubes and funnels, tonsil-like hanging globules.
Analysis of the and quadrants in Additional file 1, Figure S1 shows that the majority of the wholly disordered proteins from Crenarchaeota, Korarchaeota, Euryarchaeota, and Thaumarchaeota likely possess molten globule-like properties.
Under a fallen log is a pink slime mould (Arcyria denudata), looking like small globules of thick blood oozing from the wood.
The protein constituent of HAMLET, HLA, is a 14.2-kDa milk protein known to interact with different lipid membranes, with partially unfolded states like molten globules having increased affinity for lipid bilayers [9], [10], [11], [12].
Intact mitochondria usually appear like threads, as shown in the images at the top row, whereas fragmented mitochondria appear like small globules as shown at the bottom row.
