In addition, axon-like fascicles that grew from TTL−/− explants showed a fuzzy organization with non parallel leading processes inside the fascicles (compare high magnifications in wt and TTL−/− in Fig. 3A, C, D and F).
The arrangement of the myocyte bundles within the sleeves there appeared to be a mesh-like arrangement of muscle fascicles, made up of circular-orientated bundles that interconnected with bundles that ran in longitudinal or obliquely orientation [ 51].
Similar to the suburothelial region, these cells seemed to interconnect with each other, expanding into and throughout the smooth muscle fascicles like a network of N-cadherin+/vimentin+ processes.
We demonstrate a microscopic fabrication process based on the automated assembly of type-I collagen fibres with the ability to produce a controllable fascicle-like, structural motif allowing variable numbers of fibres per fascicle.
The tachykinin-like immunoreactivity seen in nerve fascicles and in freely dispered axonal profiles was abrogated by preabsorption with SP peptides (peptides from Santa Cruz and Sigma).
But flattening them out makes the individual fascicles accessible, like the parallel wires in old computer cables, says Dr Tyler.And by controlling the intensity and duration of the electrical pulses applied, it is possible to specify just how much of the tissue is contracted.
SP-like/NK-1R immunoreactions occurred within large nerve fascicles and frequent SP-like immunoreactive fine varicose profiles were also seen.
They peered cautiously inside, using torches they had crudely fashioned from fascicles of wild grasses.
In 1858, she began to copy out her verse and sew it carefully into fascicles, unknown to anyone until after her death in 1886.
Pathological findings showed a proliferation of atypical short spindle or oval cells with hyperchromatic nuclei and eosinophilic cytoplasm arranged in fascicles, whorls, or in a herringbone pattern with necrotic foci, associated with gaping thin-walled blood vessels displaying a hemangiopericytoma-like appearance (Fig. 2b).
Microscopic examination (hematoxylin-eosin staining) shows a proliferation of atypical short spindle or oval cells with hyperchromatic nuclei and eosinophilic cytoplasm arranged in fascicles, whorls, or in a herringbone pattern with necrotic foci, associated with gaping thin-walled blood vessels displaying a hemangiopericytoma-like appearance (b).
