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They measure 32 50 by 3-6 µm, and may be shaped somewhat like a spindle (tapered on each end) or a cylinder, or they may be flexuous (winding from side to side).
These hyaline (translucent) cells measure 30 53 long by 7.5 14 µm wide, and range in shape from somewhat like a spindle (tapering at each end, but with one end typically rounded) to subampullaceous shaped somewhat like a swollen bottle.
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Immunoblotting indicated little to no detectable levels of mitotic arrest deficient-like 1 (MaD2L1), a spindle checkpoint protein that is degraded upon activation of APC/CCdc20 after proper spindle attachment (Figure 8C).
As shown in Figure 1A, a morphological change in the cultured cells, from a cobblestone-like to a spindle-like morphology, was clearly observed even at 48 h after exposure to these cytokines.
HAECs treated with 30 mmol/L HG for 48 h showed a distinct change from a cobblestone-like to a spindle-shaped morphology.
Expression of Twist induced EMT in these cells as morphological changes from a cobble-stone-like shape to a spindle-like appearance were noted; these cells became elongated in shape and disassociated from their neighboring cells.
Forty-eight hours of exposure to TGF- β1 caused A549 cells to undergo EMT, during which the cells lost their epithelial honeycomb-like morphology and obtained a spindle-like shape.
The casing is a cardboard exterior with the discs themselves housed in an ultra-cheap plastic tray with every disc stacked on top of each other like LPs on a spindle.
After 48 h of incubation, doxorubicin transformed cobblestone-like BIU-87 cells to a spindle-like phenotype and led to loss of cell cell adhesion, which are the hallmarks of mesenchymal cells (Fig. 3a).
Hand-blown, finely tuned crystal bowls are mounted on a spindle like an angel's version of an industrial lathe.
Hard drives are stacks of disks coated with magnetic material that rotate on a spindle like an old-fashioned L.P. record.
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