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Interestingly, Best1::GFP was highly expressed in non-pigmented and lightly pigmented RPE cells, while when cells were heavily pigmented, GFP fluorescence diminished or even became undetectable (Fig. 2E c c″, d d″).
The predicted vitamin D concentration ratio for individuals with intermediate and dark pigmentation compared to lightly pigmented individuals in this study was approximately 1/√2 and 1/√3, respectively, given no additional vitamin D intake and a similar body mass index.
A total of 18 microarrays from 9 irradiated cell lines (5 from lightly pigmented donors and 4 from darkly pigmented donors) plus their corresponding unirradiated control cultures were analyzed.
We have used Affymetrix U133a v2.0 gene expression microarrays to investigate the expression profiles of a total of 9 melanocyte cell lines (5 from lightly pigmented donors and 4 from darkly pigmented donors) plus their respective unirradiated controls.
Darkly pigmented skin contains more melanin than lightly pigmented skin.
The 19-HEM cell line (lightly pigmented) was purchased from Gentaur Belgiumm), and NHEM cells (two lightly pigmented and three darkly pigmented) were purchased from Cascade Biologics (Nottinghamshire, UK).
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A significant population of cells (26%, Table 2) had 10 20 vacuoles, lightly colored with discrete deeply pigmented, spherical inclusions (Fig. 6D).
Smashbox Always Sharp Waterproof Kohl Liners, £16, smashbox.co.uk Sophisticated, densely pigmented and blendable pencils that lightly sharpen every time you remove their lid.
If it IS pigmented, dip the brush in it lightly, and tap off the excess.
At 72 hpi (MS2; Figure 1A), developing MS were easily visible, and microsclerotial mass consisting of an accumulation of brown and lightly-pigmented cells appeared on the membrane.
Our study was carried out using human melanoma cell line (G361), one of lightly-pigmented cell types shown to be highly susceptible to accumulate oxidative damage mediated by UVA irradiation [ 16].
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