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During illumination, fluorescence measurements and light dosimetry were performed.
Light dosimetry was performed using a calibrated radiometer/photometer (IL1400A, International Light, USA).
A radiometer/photometer (IL1400A, International Light, Newburyport, MA, USA) with a calibration traceable to the National Physical Laboratory (USA) was used for light dosimetry purposes.
In general, the normal occlusion time is used (4 16 hours for aminolevulinic acid and 3 hours for methylaminolevulinate). 28– 35 Light dosimetry and frequency of sessions varies significantly from one study to another.
In order to maximize bacterial inactivation and minimize inactivation of host neutrophils, an intra-articular injection of Photofrin instead of intravenous administration was used and the light dosimetry was optimized to treat arthritis induced by MRSA infection [ 42].
The observed correlations support the hypothesis that non-invasive in vivo LIFS provide real-time information useful for adapting light dosimetry for each patient treated by PDT, in order to avoid under or over treatment and undesirable side effects.
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This combination of light delivery and dosimetry is well suited for adjuvant treatment with PDT in malignant pleural tumours.
Data were collected from 130 workstations using questionnaire and physical measurements of the noise (noise dosimetry), lighting (task area illuminance) and heat (wet bulb globe temperature – WBGT) levels.
The goal of this work is to evaluate the performance of a commercial flatbed scanner with LED based source light for radiochromic film dosimetry.
In situ dosimetry ensures optimal light distribution and allows total doses (incident plus scattered light) to be monitored at different positions within the cavity.
Hence, selectivity is provided not only by the pharmacokinetics of the photosensitizer but also by the dosimetry of the activation light, practically eliminating the systemic toxicity.
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