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The accompanying evidence on exposure to endogenous and exogenous oestrogen indicates that the lifetime length of exposure to endogenous oestrogen has been increasing, which is consistent with upward trends in incidence of breast cancer, particularly in developed countries.
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Importantly, the relationship between telomere length and lifetime duration of depression was significant after age was controlled, indicating that longer exposure to depression was not simply a proxy for more advanced age, which is also associated with telomere shortening.
Each participant was asked about current and past residences throughout her lifetime, including length of time residing at each residence (measured by dates of move-in and move-out).
We also examined the impact of antidepressant treatment on the relationship between lifetime duration of depression and telomere length.
Telomere length within the entire depressed group was significantly inversely correlated with lifetime depression duration (controlling for age and sex); individuals with greater lifetime duration of major depression had significantly shorter telomeres (F = 4.70, p<0.05) (Fig. 1).
We define path lifetime as the length of each period during which an end-to-end path does not suffer link failures.
In all cases, the increase of plain and cold expanded hole diameter from 8 mm to 10 mm increases crack initiation lifetime with a length of c1 = 0.25 mm and 0.5 mm.
We could not detect any significant dependence (fig. S6): the lifetime and maximal length of the invaginations were similar across depletion times.
In addition, this scheme can regulate the data lifetime dynamically and optimize the length of the lifetime based on network parameters.
The time horizon used is the patients' estimated lifetimes and the length of each cycle is one year.
Survival analysis applied to sleep bout durations, in which lifetime refers to the length of time spent in a given stage, indicates decreased stability of sleep in OSA patients in proportion to severity of disease[14].
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