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Given that the silicon bulk lifetime is sensitive to high temperatures, ALD Al2O3 has a natural advantage over thermal SiO2 in terms of integration into industrial cell processes.
Since fluorescence lifetime is sensitive to the physico-chemical environment such as the membrane potential, pH and osmotic conditions [26], [27], lifetime analysis can be used to assess biomolecular interactions and localization of targets in different microenvironments.
Both in vitro (lysate) and in situ (intact RBC) calibrations using the fluorophore calcein (Figs. 3 and 4) proved that fluorescence lifetime is sensitive to the local hemoglobin concentration.
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FLIM is an excellent method to probe the environment of a molecule, because excited-state lifetimes are sensitive to environmental changes such as pH, viscosity, oxygen concentration and refractive index.
The CREL signal from PtG4 has a lifetime which is sensitive to tissue background pO2 level at the point where the luminescence emission is generated.
It was predicted theoretically that the exciton decay lifetime of QDs is sensitive to temperature [19].
Low cycle fatigue lifetime is very sensitive to the cyclic strain amplitude, and decreases drastically with the increasing of cyclic strain amplitude.
The fluorescence lifetime is also sensitive to the local environment of the QDs.
The lifetime is more sensitive concerning the temperature for the first stage of the thermal decomposition of chitin.
On the other hand, fluorescence lifetime is neither sensitive to the intensity of excitation light nor concentration of fluorophores, and this is one of the main advantages of fluorescence lifetime over fluorescence intensity measurements (Fig. 4).
For the individual insect, however, the predation pressure may not be constant over its lifetime, and if it is sensitive to changes in predation risk it should adapt its decisions for the amount of public and private signalling to these changes.
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