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The inter-rater reliability was found to be good: Cohen kappa coefficient was 0.89 for the presence of any current or lifetime Axis I disorder.
In addition, controls had no lifetime axis I DSM diagnosis and no positive family history of schizophrenia or bipolar disorder spectrum disorders.
Psychiatric comorbidity was significant with a group mean of 1.9 lifetime Axis I diagnoses (SD = 1.1).
There was high to very high between-study heterogeneity for lifetime Axis I disorders.
We found a significantly higher mean number of lifetime Axis I disorders in the PD group.
Relapsers had significantly more lifetime Axis I disorders, especially major depression and agoraphobia.
Similar(35)
Patients with instable ED diagnoses had lifetime axis-I comorbidity more frequently than patients with stable ED diagnoses (80.7% vs. 65.8%, χ = 4.74, df = 1, p < 0.05).
Patients with instable ED diagnoses had lifetime axis-I comorbidity more frequently than patients with stable ED diagnoses (χ = 4.74, df = 1, p < 0.05).
The results of the present study indicate a relevant role of the presence of lifetime axis-I psychiatric comorbidity regarding the stability of the ED diagnoses during an observation time of 30 months.
Lifetime psychiatric axis I comorbidity was very common, most notably mood and anxiety disorders, but also ADHD and psychotic disorders.
All respondents were assessed with the SCID-I (Spitzer et al. 1992) for current and lifetime DSM-IV axis I diagnoses, subtype of BD and the number of symptoms experienced during the mood episodes.
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