Sentence examples for lifespan prolonging from inspiring English sources

Similarly, lifespan extension by CIN was also blocked in mutants of serotonin receptors (ser-1) and anti-oxidative enzyme (mev-1) (Fig. 1C&D, Table 5), suggesting that CIN requires the insulin signaling pathway, anti-oxidative pathway and serotonin signaling for its lifespan prolonging effect.

Strong doubts over the lifespan prolonging effect of Sir2 overexpression have recently been expressed [ 18].

Also, several studies indicate a health and lifespan prolonging effects of high proteasome activity.

Marginal survival has been reported in severely impaired or bedridden patients [ 18, 24, 30], as well as in patients with no lifespan prolonging anticancer therapy [ 19].

It is also possible that the lifespan prolonging activity of ER is not due to its effect on a single gene rather than on a cluster of genes involved in oxidative stress, IIS pathway, apoptotic pathway, programmed autophagy, and the olfactory system.

Our study demonstrated its lifespan prolonging, anti-stress and anti-proteotoxicity effects in an organism.

However, the fact that aggregation and toxic effects in cell culture and hippocampal slices are inhibited and that locomotor activity is improved and the lifespan prolonged in Drosophila melanogaster in the presence of ligands that bind to and stabilize a region in Aβ in an α-helical conformation [ 110] supports the on-pathway paradigm.

We found that metformin increases nematode healthspan, slowing lipofuscin accumulation, extending median lifespan, and prolonging youthful locomotory ability in a dose-dependent manner.

That means both rural areas and megacities alike will welcome tech whose lifespan is prolonged by solar power.

When subjected to caloric restriction, resveratrol treatment as well as lowering of ambient water temperature, the expression rate of these markers was delayed while lifespan was prolonged [24], [25], [26], [27], [28].

Yeast kept at cold temperatures has a massively reduced growth- and metabolic rates; at 10°C the chronological lifespan is prolonged [ 9].