Sentence examples for lifespan prolongation from inspiring English sources

Several studies have demonstrated that systems involved in nutrient level sensing are central for CR mediated lifespan prolongation and thus being relevant for ageing related processes in general.

Numerous studies have demonstrated the pivotal role of SIRT1 in lifespan prolongation in various species via regulating epigenetic and genetic events.

Interestingly, the herbal formula SQDB prolonged life span in ser-1 mutant worms (Table 5 & 6), suggesting that the serotonin pathway may not be involved in lifespan prolongation by SQDB.

Sirtuins were investigated for their contribution to lifespan prolongation under caloric restriction conditions in lower organisms [ 4, 46].

Lamming et al. [ 4] have shown that decreased mTORC1 signaling is sufficient for lifespan prolongation independently from changes in glucose homeostasis.

Lifespan prolongation was accompanied by increased body-weight over time, which was similar to, albeit less than, wt littermates (Fig 1G).

**as opposed to life prolongation or curation.

Apart from the effect of prolongation of lifespan by antioxidant administration throughout most of the lifetime (long-lasting experiments), another approach to study antiaging effect of antioxidants consists in short-time experiments, in which functional tests compare the status of experimental animals before and after supplementation.

Furthermore, LACE produced higher prolongation of lifespan in tumor-bearing mice (Fig. 8).

Only in some cases considerable prolongation of lifespan was obtained and in organisms which are evolutionarily quite distant from mammals.

In flies expressing wild-type Aβ1 42 we were able to confirm the prolongation of lifespan by the heavy and light chains of ferritin and the toxic effect of SOD1 (data not shown).