Sentence examples for lifespan in parallel from inspiring English sources

Collectively, these findings indicate that frh-1 RNAi extends lifespan in parallel to CR-related pathways, independently of AMPKs, major regulators of energy metabolism.

JNK-1, the C. elegans homolog of mammalian JNK, is thought to regulate lifespan in parallel to the IIS pathway, by regulating the subcellular localization of DAF-16 [ 119].

Using Drosophila as our model system, we found that lamotrigine decreased mortality and increased lifespan in parallel with a reduction in locomotor activity and a trend towards metabolic rate depression.

Two lifestyle adaptations, caloric restriction and exercise (Jang et al., 2012; Valdez et al., 2010), have been consistently demonstrated to extend lifespan and, in parallel, to mitigate age-related alterations of NMJ.

As long-lived mutants and mutants with normal lifespan are often morphologically indistinguishable, the barcode approach to monitor the length of lifespan of many mutants in parallel demonstrated the power of parallel analysis for detecting weak phenotypes.

We propose that MDT-15's function in ROS defense may also underlie its lifespan promoting role, perhaps in parallel to mdt-15-dependent lipid signaling.

In principle, it should be possible to continue useful careers for longer, seeing as "healthy life expectancy" has tended to rise in parallel with lifespans as a whole.

Our results indicate that tph-1 and daf-7 are likely to act in parallel to modulate lifespan in response to food, and that their mutual regulation represents crosstalk between these two pathways.

Despite this difference, however, loss of GH / IGF-I signaling in mice has effects on lifespan that parallel loss of IIS in C. elegans and Drosophila, as exemplified by a series of long-lived dwarf mouse models, including the GH-deficient Pit1 dw/ dw) ("Snell") and Prop1 df/ df) ("Ames") mice, the GH-insensitive Ghr mice, and the PappA mouse with localized reductions in IGF-I signaling [ 25].

2) The authors repeatedly argued that 5-HT and DAF-7 act in parallel to modulate the lifespan.

In parallelizing, we assert these in parallel.