Sentence examples for lifespan barriers from inspiring English sources

Exploiting these insights into proliferative lifespan barriers in HCEC will underpin the development of novel strategies for cell-based therapies in the human cornea.

Whilst it is possible that senescent cells may contribute to age-related ocular pathologies (Faragher et al., 1997b), it is clear that there is a practical need to understand the proliferative lifespan barriers operating within HCEC in vitro to manufacture utile cell lines for both fundamental study and translational use.

The exact nature of the second parallel signal(s) that act to limit HCEC proliferation in concert with telomere erosion is unclear, but could be dissected through additional studies using HCEC cultured under different conditions, and with different proliferative lifespan barriers ablated.

These results agree with previously published PRB field data and simultaneously conducted geochemical monitoring and mass balance calculation, indicating that both the geochemical and hydraulic environment of the PRB play an important role in determining barrier lifespan.

In both stories, differences in lifespan and other insurmountable barriers mar their relationships and attempts to understand each other.

Likewise, the stabilised multilayer films with barrier experience a shorter lifespan, than the multilayer stabilised PE films without barrier layers.

Findings from Phase 1 of these interviews (i.e., enablers and barriers to the development and implementation of the LIFEspan model) have been reported [ 38].

Thermal cycling lifespan of novel rare earth magnesium hexaaluminate (REMHA) based thermal barrier coatings (TBCs) such as lanthanum magnesium hexaaluminate (LMHA), neodymium doped LMHA (LNMHA) and LNMHA-yttrium aluminium garnet (YAG) composite was tested using gas burner rig operating at 1400 °C.

In this work, Taguchi design method based GRA used to optimize TC of TBCs at high-temperature application parameters for multiple response quality features such as TD and TFC to withstand high temperature in studying the amount of barrier offered (temperature drop occurring across the coating) and lifespan of coatings over the metal substrate.

HLRWs are going to be placed in deep geological repositories, enveloped in an engineered bentonite barrier, whose physical conditions are subjected to change throughout the lifespan of the infrastructure.

Nonetheless, in most reports the additional lifespan of the post-senescent cell lines expressing SV40LT is still restricted by another barrier called crisis.