Sentence examples for lifecycle pathways from inspiring English sources

We can elaborate ISEA to include higher granularity components and mechanisms that map to subcellular details such as cell lifecycle pathways and intercellular signaling networks when validation against an expanded set of targeted attributes requires doing so.

Regulatory pathways that govern the lifecycle of MAP appear to be specified by tissue and cell type.

24 There are conflicting reports on the effect of TGF-β on HCV replication 25, 26; however, a recent small interfering RNA (siRNA) screen to identify host pathways in the viral lifecycle reported that Smad5 knockdown significantly reduced HCV replication.

Because of the intimate relationship between L1 activity and multiple cellular processes, it is likely that people with genetic backgrounds that produce defects in any of the pathways influencing the L1 lifecycle are more vulnerable to insult from TEs.

Using genome-wide RNA interference screening, we found that this step in the viral lifecycle requires at least two host encoded pathways: the coat protein complex I (COPI) coatamer and fatty acid biosynthesis.

Understanding the governance of gene expression and regulation within these families, e.g. via interactions with the TgAP2 family of transcriptional regulators, may prove key to dissecting the full panorama of pathways that regulate the definitive coccidian lifecycle and aid in the complete and accurate annotation of the T. gondii genome database.

Whether other 5-HT2AR-associated downstream pathway would be involved in HCV lifecycle needs further investigation.

Individual genes, gene ontologies and pathways that are modulated during the parasite lifecycle were also profiled.

The range of parasites with specific lifecycles, target tissues, and unique gene products to modulate host pathways is an incredibly rich experimental vein to tap.

Up-regulation of components of this pathway may reflect increased metabolism in the aquatic lifecycle stages where considerable tissue/cellular remodelling is required.

This allows us to examine the variability in levels of transcript abundance between different compartments in a single linked pathway that should be required throughout the parasite lifecycle.