Fever from a life threatening cause is defined as fever that is associated with neck stiffness, extreme weakness or inability to stand, lethargy, unconsciousness, convulsions, severe abdominal pain, or respiratory distress.
For those with fever from a life threatening cause, the guideline recommends assessment of temperature and blood pressure and quick establishment of intravenous access, so that fluids and antimicrobial agents can be given if the patient is in shock or if sepsis is suspected.
Recognize life threatening causes of altered contrast dynamics such as cardiac asystole.
Severity of AEs will be graded on a five-point scale (Mild, Moderate, Severe, Life threatening, causing death).
Serious adverse events (SAEs) are defined as any event that is fatal, life threatening, causes or prolongs hospitalization; causes disability or incapacity or requires medical intervention to prevent permanent impairment or damage, or any grade 4 toxicity.
Deaths occurring during follow-up; Serious adverse events (life threatening, causing admission to hospital, or discontinuation of treatment); Haematological and biochemical adverse effects (for example, neutropenia, liver toxicity); Early vomiting; Other adverse events.
An AE was considered serious (SAE) if it was life threatening, caused permanent harm, resulted in hospitalization or extension of in-patient hospital treatment, or was considered to be medically relevant by the investigator.
Barbiturates, methamphetamines, cocaine and crack, benzodiazepines, and alcohol withdrawal can all be life threatening, causing seizures, and in the case of cocaine and crack, respiratory failure, stroke, and convulsions.
Severe: fatal or potentially life threatening or causing permanent disability.
The classification used for ADRs was as follows [ 6, 10]: Severe: fatal or potentially life threatening or causing permanent disability.
Learn about VAS, vaccine associated sarcoma, a life threatening cancer caused by giving vaccines.
