One aspect of specific added value in the Whitehall MRI substudy will be the availability of a fine-grained chronological clinical and life-style record with very detailed cognitive assessment and comprehensive MRI data covering structural and functional brain connectivity.
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Information about life style factors was sometimes incompletely recorded in the files.
We recorded demographic features, life style factors comprising alcohol use (at least one unit per month) and exercise (at least once per month) that included time spent in walking, for example, to reach public transportation, and cardiovascular and non-steroidal anti-inflammatory drug (NSAID) use.
Medical history and life style characteristics were retrieved from dedicated case record forms.
Information on hospital discharge diagnoses, underlying diseases, life style and risk conditions were obtained from medical records and, with regard to cases, also from hospital medical records.
"The key to my kind of life style is to walk slow," said Mr. Mintzer, a composer, arranger, performer, recording artist and teacher.
Data pertaining to life style, occupation, duration of stay in HLNRA, habits etc. are recorded in proformae designed under the World Health Organization (WHO) guidelines.
Data recorded in THIN include demographics, diagnoses, symptoms, prescriptions, life style information such as smoking or alcohol consumption, test results, height, weight, referrals to hospitals and specialists, and, on request, specialist letters and hospital discharge summaries.
History of mental illness, present symptoms, life style, and pharmacological treatment were obtained from interview with the patient, with additional information collected from treatment records and clinical staff.
