Sentence examples for life span without from inspiring English sources

The drug, in other words, helped the fat mice enjoy more of their available life span without increasing the span itself.

It may be the ultimate free lunch — how to reap all the advantages of a calorically restricted diet, including freedom from disease and an extended healthy life span, without eating one fewer calorie.

In the case of the evolutionary approach, Rose says that people who wanted to take his pill regime later in life might still be able to achieve an appreciable — if much less dramatic — increase in life span without giving up their youth.

However, not every DNA repair deficiency creates exactly the predicted effects; mice deficient in the NER pathway exhibited shortened life span without correspondingly higher rates of mutation.

Furthermore, infection can lead to clinical disease after a lengthy incubation period, or be sub-clinical, in which case the infected person will continue to live to the end of their natural life span without any symptoms.

Mutations in the Indy gene (for I'm not dead yet) were first described in flies where they dramatically extend life span without a loss in fertility, physical activity, flight velocity or metabolic rate [ 1, 2].

So why do chimpanzees make it through their entire normal life spans without significant brain shrinkage, whereas the human brain appears to wither with age? "This is the million-dollar question," Sherwood says.

The goal is to it change people's quality of life so we can live whatever a normal life span is without massive disease.

Heterozygosity for P{lacW} transgene insertion at the Indy locus has been shown to result in life span extension without a decrement in fecundity under normal laboratory culture conditions, but with a distinct cost under reduced caloric intake [ 13].

In contrast, subsequent reports demonstrated that 2.5-fold, 3-fold, and 5-fold increased expression of dSir2 from the native dSir2 locus results in life span extension without an increase in dnaJ-H mRNA expression [ 6, 7].

In coincidence with this idea, we found that the suppression of TDP-43 in the Drosophila glia provoked serious locomotive defects with functional alterations in synaptic transmission followed by early neurodegeneration and reduced life span but, without affecting the number or the survival rate of glial cells in vivo (Supplementary Material, Fig. S1E G) (9).