And the "Journal" became an account, not of a peaceful and civilised life, but of response to intense pressure.
"Most everyone walking past sort of shrugged and gave the usual 'get a life' kind of response, which I find so tedious," Ms. Truss said.
Secondary end points included tolerability, quality of life, duration of response, time to disease progression and overall survival assessed from the time of initiation of therapy.
But if someone is vulnerable for another reason — perhaps a tragedy experienced earlier in life — this kind of response might be activated.
Secondary endpoints include disease-free survival, toxicity, health-related quality of life (HRQL), prediction of response and recurrence risk assessed by genomic and expression profiling.
The primary endpoint is overall survival, secondary endpoints are disease-free survival (DFS), toxicity, health-related quality of life (HRQL), prediction of response, and recurrence risk assessed by genomic and expression profiling.
The current study provided important information about Bahraini breast cancer survivors with several strengths including randomized sampling method, use of standardized measures of quality of life, a satisfactory response rate of 71%, and the use of a clinically meaningful analysis.
The main trial showed de Gramont and Lokich to be equally effective in terms of survival, quality of life and response rates but Lokich had higher toxicity and hand-foot syndrome.
In conclusion, the complete management of CM and MOH patients derives from an array of synergistic and multidisciplinary interventions aimed to improve patient's quality of life, response to treatments and clinical outcome.
As secondary objectives we will study PFS, quality of life, treatment response on neoadjuvant chemotherapy, morbidity of surgery and resection rate, and whether CEA can predict for treatment response, PFS, and OS.
