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"life of despair" is correct and usable in written English.
You can use it when describing a difficult or hopeless situation. For example: "After the long journey, they were met with a life of despair."
Exact(5)
This leads them to live a life of despair, which destroys them and their communities and leaves us continuing to wonder why they make disempowering choices.
But under this new approach, Nariman, who last month lay burbling in a cot he shared with a pink teddy bear, gaining weight and being cooed over by nurses, waited not for death or a life of despair but for placement in a foster home and eventually a family to take him permanently.
It is often the difference between life and death, or between a productive recovery and a life of despair.
With violence spiking in certain areas of Colombia, a project spearheaded by international star Juanes seeks to eschew a likely life of despair and an education in war for the country's children – in exchange for a foundation in peace building and hope.
PMTCT services can turn a life of despair into a life of hope, as the story of Edward and Witness shows.
Similar(55)
This is Bellow's Augie March recounting how he fell in love with books: I had no eye, ear, or interest for anything else — that is, for usual, second-order, oatmeal, mere-phenomenal, snarled-shoelace-carfare-laundry-ticket plainness, unspecified dismalness, unknown captivities; the life of despair-harness, or the life of organization-habits which is meant to supplant accidents with calm abiding.
Many women are fighting internal wars that we cannot see, except perhaps when they take their own life out of despair.
Think about the less fortunate and inspire gratitude in your life instead of despair.
Within a few minutes Mac reveals that he wants Huey to kill him, ending a life of deep despair.
Nathaniel Ayers presented a remarkably compelling story – here was a man with an almost preternatural gift for music, struck at an early age by schizophrenia and reduced to a life of quiet despair, despite his undiminished talent, on the streets of LA's Skid Row.
(Homer interprets his brother's theory as Langley's "bitterness of life or despair of it").
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com