Sentence examples for life cycle progression from inspiring English sources
In the previous study, life cycle progression of Pfpuf2 parasites beyond gametocytogenesis was not analyzed [22].
Together these data exclude a vital role for Plrx in Plasmodium life cycle progression under standard conditions.
Successful generation of Plrx mutants permitted a detailed observation of the in vivo function of Plrx during life cycle progression of the malaria parasite.
The successful generation of plasmoredoxin knockout mutants in the rodent model malaria parasite and phenotypic analysis during life cycle progression revealed a non-vital role in vivo.
The corresponding predicted experimental outcomes are refractoriness to gene targeting, which would correlate with a vital role in asexual blood stage development, or a detectable phenotype during life cycle progression, respectively.
Recently however, a family of genes related to the plant Apetala-2 (AP2) transcription factors has been identified in Plasmodium and related apicomplexan parasites [6], [7], and proposed to play a central role during life cycle progression.
Because they are critical to the life-cycle progression of many pathogenic protozoa, they represent potential targets for selective inhibitors.
ACs are the subject of particular interest as cAMP is thought to influence the life-cycle progression of T. brucei [24], and understanding of ACs may provide insight into the mechanism of parasite development and transmission.
These data suggest that significant transcriptional level remodelling of the membrane trafficking system accompanies life-cycle progression in trypanosomes.
The human-to-mosquito transmission triggers important molecular changes in the gametocytes, which initiate gametogenesis and prepare the parasite for life-cycle progression in the insect vector.
Current therapies have limited efficacy and numerous side effects [ 4] and a major challenge in translational hepatology research is the development of new approaches that target critical processes in the HCV life cycle and progression to disease state.
