Excessive levels of hexavalent chromium were also found at the entrance to Huangnibao Reservoir, which lies downstream of Chachong.
This signalled that the target of malacidin, like that of friulimicin, lies downstream of UDP-MurNAc-pentapeptide formation.
Inhibition of RSK1 (SL0101), which lies downstream of ERK and also phosphorylates TSC2, similarly did not inhibit the TGF-β1 collagen response (Supplementary Fig. 4e).
The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G-protein coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+).
In January 2012 the town of Carolina, which lies downstream of major coal mines, lost its entire municipal water supply overnight when a huge volume of acid mine drainage was washed into its drinking water reservoir by heavy rains.
Since, the expression of vitamin D receptor (VDR) in cells with Flt3 mutations was increased to the same extent as in other AML cells this suggests that failure of these cells to differentiate lies downstream of the receptor.
The brn1/2/4 gene lies downstream of the regulatory genes executing post-gastrular specification of the midgut, as shown by further gene expression perturbation experiments which provide an initial glimpse of the underlying network architecture.
Since Rfx6 lies downstream of Ngn3 and upstream of other islet transcription factors, a comprehensive understanding of the role of Rfx6 could aid the generation of β-cells from patients with DM[51].
Considering that Wnt signaling lies downstream of Kindlin-1 [17], we next investigated the expression of Wnt-10a in the DRG, spinal cord, and hippocampal regions of animals from different experimental groups.
These results imply that Cby lies downstream of Foxj1 in ciliated cells.
This is indicative of a block in division that lies downstream of FtsZ assembly.
