Sentence examples for lie upstream of from inspiring English sources

They may bind directly to special "promoter" regions of DNA, which lie upstream of the coding region in a gene, or directly to the RNA polymerase molecule.

Sequences required for full activation lie upstream of the transcription initiation site and are distinct from sequences necessary for basal expression.

Thus, SSA has been suggested to lie upstream of MMN generation.

This finding suggests that extrinsic signaling pathways may lie upstream of the network of known transcription factors that regulate pluripotency.

Moreover, only Meg8 transcripts have the intron-encoded microRNAs miR-341, miR-1188, and miR-370 that lie upstream of Irm (see Figure 2 and Table 2).

These results further support our hypothesis that oxidative stress is proangiogenic and is likely to lie upstream of the pathogenesis of RNV in the Vldlr-/ mouse.

RhoA lies upstream of MLC-2 and controls MLC-2 activation.

In the control of the AER, Wnt3 lies upstream of BMP ligands (Barrow et al., 2003) and Dkk1 interacts with BMPs in this context, as they can mutually induce each others expression (Mukhopadhyay et al., 2001; Grotewold and Rüther, 2002).

The region of peak association lies upstream of LOXL1-AS1, a long non-coding RNA (lncRNA) encoded on the opposite strand of LOXL1.

We identified potential −35 and −10 sequences and a dyad symmetrical sequence lying upstream of pMR68 merR and upstream of merT1, respectively; these sequences may represent putative promoters of the mer operon of cluster 1 in pMR68.

These results suggest that the generation of ROS by Nox4 lies upstream of GADD153.