The WT amino acids, G151 and L168, lie at highly conserved positions in and near the ion selectivity filter, and these mutations reduce channel selectivity.
Three disease-causing mutations in strumpellin have been described, V626F, L619F and N471D, and all lie in highly conserved sequences [8].
However, when both ends of AR lie in highly repetitive regions, there will be too many SRs involved in the local assembly process, which makes local assembly extremely slow and it is difficult to distinguish the correct PS sequences from thousands of possible paths.
This technique allows a clear representation of sets of data lying in highly dimensional spaces.
MIT researchers find that the key to purple bacteria's light-harvesting prowess lies in highly symmetrical molecules.
The future of the British military lies in highly trained computer programmers, probably no more than 12 of them.
Atop the simple structure of the Cheshire Plain, however, lies a highly fragmented pattern of glacial clays, sands, and gravels, meandering rivers, and scattered distinctive small lakes, or meres.
"When unrealistic and outmoded regulation results in our having to lay off highly trained workers and constrains our investment in our networks, it is a disservice to all local-phone users in the states we serve," Whitacre said in the statement.
My home country Kiribati is a series of beautiful atoll islands, which are very low lying and highly vulnerable to the impacts of climate change, particularly that of sea level rise.
Almost exactly halfway between the divergently transcribed mgx and simA genes (162 bp upstream from the simA start codon ) lies a highly conserved 51 bp region, identical in isolates K288, 9117, 02161A and QMA00131 [29] (Fig. 4).
