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Nevertheless, given the fact that many independent mutations in different human ORC subunits, where some have been shown to affect replication functions directly, and hypomorphic mutations in the ATR replication check point protein lead to primordial dwarfism, it is hard to escape the inference that loss of ORC replication licensing functions are indeed epistatic to the MGS phenotype.
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How might Asl perform this primary licensing function?
In this way, the license functions as a social contract between everyone to arrange an immediate return on investment.
Sections from 17 benign lesions and 55 carcinomas were immunostained with anti DMBT1 antibody (DMBTh12) and sections from 36 samples, were double-stained also with anti MCM5, one of the 6 pre-replicative complex proteins with cell proliferation-licensing functions.
NK cell licensing and function are dependent on the expression and signaling balance of various activating and inhibitory receptors which are acquired at different times during NK cell maturation (Kim et al., 2002).
You can still get a driver's license and function just fine without residency, while keeping your options open.
This September, local authorities closed the venue, claiming that it didn't have the license to function as a nightclub.
The business wasn't truly a university; it offered no degrees and never obtained a state license to function as an educational institution.
The prospect of having the department's advocacy, licensing and inspection functions dispersed among several remaining departments also bothers them.
The one-year programme will cover a wide range of areas, including managerial and marketing skills such as product development, legal issues such as patents and licensing, and core functions such as finance, production and human resources.
It's more than that, though: without modernization in this area, services that increasingly rely on connectivity as an adjunct to their functions (licensing, law enforcement, hospitals) will suffer and the standard of living will truly be lower.
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