Sentence examples for library targets from inspiring English sources

The libraries were screened using standard colony picking and liquid handling robots in a work flow designed to identify any forms of the soluble library targets and, where found, determine whether they bound the bait protein (Fig. 2).

The main drawback is the non-specificity of the library targets which necessitates secondary screens for elimination of general toxicity compounds as opposed to those targeting specifically the virulence system.

The siRNA library targets ~2,400 unique human genes, with three siRNAs per gene, as described previously[ 30].

We added adapters in approximately 15-fold excess of library targets, and removed un-ligated adapters and adapter-dimers using 1.0X AmpureXP SPRI bead purification (Agencourt).

This focused library targets each protein-coding gene with ∼25 independent shRNAs and contains a large set (>1000) of negative-control shRNAs.

The GATB library targets standard computing resources such as current multicore processor (laptop computer, small server) with a few gigabytes of memory.

In this regard, a completely random shRNA library targeting all the genes with known or unknown sequences is of priority.

These efforts, including the preceding, mandatory in vitro characterization of this compound library, target validation and animal model validation, will be described elsewhere by Sanofi affiliated researchers.

Starting from the high-level description of a system, a Markov reward model is constructed from the Control Data Flow Graph (CDFG) and a component characterization library targeting FPGAs.

Since loss of essential genes is uniformly toxic in CRISPR-based screens, we also developed a small hairpin RNA (shRNA) library targeting essential genes.

The combination of the 3,5-bis trifluoromethyl phenyl group with a spirohydantoin motive as a central scaffold was the basis for the design of a combinatorial library targeted towards the neurokinin-1 receptor.