TableCurve2D enabled the identification of the simplest and more appropriate functions to describe the data by fitting the data to a library of thousands of trial functions and categorizing the results according to the goodness of fit.
The designs described by these 96 papers, and the corresponding narrative summaries, formed the library of phase II trial designs around which the guidance manual was developed.
The process is simple and free, at least for the public-facing databases Omnity has assembled, comprising U.S. patents, SEC filings, PubMed papers, clinical trials, Library of Congress collections and more.
Interestingly, these drugs were identified as inhibitors of HIF-1 α protein translation and HIF-2 α mRNA expression in a cell-based screen of a library of drugs in clinical trials.
We searched the register of trials in Cochrane library from 1996 to end of 2004.
This was used to search the register of trials in Cochrane library between the years 1996 to end of 2004.
The researchers performed a systemic literature retrieval using electronic databases including PubMed (1966-2010), English medical Current Contents (EMCC 1995-2010), ChiNationalnal Knowledge Infrastructure (CNKI 1979-2010), CHospital Knowledge Databaseabase (CHKD 1994-2010) and the Cochrane library clinical trials registry (Issue 3 of 4, Jul 2010).
A systematic literature review was performed of phase II clinical trial methodology to produce a detailed library of available phase II designs applicable to cancer trials.
We searched the Cochrane Menstrual Disorders and Subfertility Specialized Register (10 April 2013), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2013, Issue 1), MEDLINE (1950 to 4 April 2013), EMBASE (1974 to 4 April 2013), and other electronic databases of trials including trial registers, sources of unpublished literature, and reference lists.
They have completed a portfolio of systematic reviews (published in The Cochrane Library) of the evidence from relevant randomised controlled trials (RCTs).
We undertook a systematic review of the published literature, searching PubMed and the Cochrane Library, of trials and reviews (N = 230) that reported stillbirth or perinatal mortality outcomes for eight interventions delivered during labour.
